IMMUNOGENIC PROPERTIES OF INACTIVATED VACCINE AGAINST POULTRY PASTEURELLOSIS FROM STRAIN A 46 N576
The article presents the results of immunogenic properties of inactivated vaccine against avian pasteurellosis from strain A 46 No. 576.
As a result of studying the vaccine prepared from field isolates of Pasteurella Ch-1, K-1 and deposited strain A 46 № 576 after the addition of 6% gel of aluminum oxide hydrate after 12 months of study.
The prepared vaccine from field isolate Ch-1 with 6% aluminum oxide hydrate gel had 66% CIE after 3 months, 62% after 6 months and 58% after 12 months. Vaccine from Pasteurella multocida A 46 #576 with 6% aluminum oxide hydrate gel had 100% CIE after 3 and 6 months and 99% after 12 months. Vaccination with strain K-1 resulted in a lower percentage of KIE: 78%, 74%, and 69% after 12 months, respectively. Thus, the vaccine made from Pasteurella multocida A 46 #576 showed the highest immunologic efficacy index (IEI) of 99% with prolongation up to 12 months, compared to bacteria prepared from Ch-1 and K-1.
The protective properties of inactivated vaccines with adjuvant also remained at 12 months (observation period). The inactivated vaccine from strain A 46 No. 576 showed the highest values.
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