Login | Register
Kazakh National Agrarian Research University ISSN 2304-3334 (Print)  ·  ISSN 2304-3334 (Online)
submit an article
Menu
submit an article
STOCK-RAISING AND VETERINARY

THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS

T.V. Yanich* 1 , M.A. Derkho 1

1 South Ural State Agrarian University, Troitsk, Russian Federation

doi.org/10.37884/2-2022/01 pp. 5-12 Admitted 27.05.2022 Published 28.06.2022

Abstract

A quantitative assessment of erythrocyte homeostasis in the body of Holstein heifers and its relationship with the amount of steroid hormones - cortisol and progesterone is given. Blood was taken from heifers of the experimental group (n=10) at 3, 6, 9, 12, 15 months of age. The number of erythrocytes, hemoglobin and hematocrit by the age of 15 months increases by 36.33; 12.93 and 40.18%. At the same time, the volumetric characteristics of erythrocytes (average erythrocyte volume, erythrocyte distribution index by volume) practically do not depend on age, but their saturation with hemoglobin (average hemoglobin content in an erythrocyte, average hemoglobin concentration in an erythrocyte) decreases. The level of steroid hormones - progesterone and cortisol in the blood of heifers increases with age by 46.06 and 8.24 times (p≤0.05). At the same time, the concentration of cortisol statistically significantly correlates with the number of erythrocytes (r=0.71 - 0.95), the value of the index of distribution of erythrocytes by volume (r=0.74 - 0.98). The level of progesterone, starting from the age of 9 months, as well as erythrocytes (r=0.82 - 0.93) and hemoglobin (r=0.63 - 0.73). The results obtained allow us to judge the close relationship between the cellular composition of the blood and steoid hormones. Therefore, further study of this issue is relevant.

heifers; cortisol; progesterone; correlation; erythrocytes, blood composition, hemostasis, hemoglobin

01 Introduction

The full text of the article is available for download in PDF format on the right panel.

02 References

  1. 1.Wang Y. The Relationship between Erythrocytes and Diabetes Mellitus / Y.Wang, P.Yang, Z.Yan, Z.Liu, Q.Ma, Z.Zhang, Y.Wang, Y.Su // J Diabetes Res. –2021. –Vol. 25.–Р.1-9.
  2. 2. Bryk A.H. Quantitative Analysis of Human Red Blood Cell Proteome/ A.H.Bryk, J.R. Wiśniewski // J Proteome Res.– 2017.–Vol.16(8). –Р.2752-2761.
  3. 3. Yuan Y. Tissue-Specific Rhythmic Recruitment Pattern of Leukocyte Subsets / Y.Yuan, S.Wu, W.Li, W. A.He // FrontImmunol. –2020. –Vol.11. –Р.1-8.
  4. 4. Yanich T.V., Derkho M.A., Tegza A. Hemostatic Profile of Holstein Heifers Depending on Age // International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies. –2022.–Vol. 13(1).–Р.2-11.
  5. 5.Kosmachevskaya O.V. Alternate and Additional Functions of Erythrocyte Hemoglobin/ O.V.Kosmachevskaya, A.F. Topunov // Biochemistry (Mosc). –2018.–Vol. 83(12).–Р.1575-1593.
  6. 6.Higgins J.M. Red blood cell population dynamics // Clin Lab Med. –2015.–Vol. 35(1). –Р.43-57.
  7. 7.Karsten E. Red blood cells are dynamic reservoirs of cytokines/ E.Karsten, E.Breen, B.R. Herbert // Sci Rep. –2018.–Vol.8(1). –Р.1-12.
  8. 8. Baskurt O.K. Comparative hemorheology / O.K.Baskurt, H.J. Meiselman // ClinHemorheolMicrocirc. –2013. –Vol.53(1-2). –Р.61-70
  9. 9. ЧугуновА.В.Қызыл дала тұқымды бұзаулары қанының морфологиялық және биохимиялық көрсеткіштері/ А.В. Чугунова, Л.Н. Захарова // Қиыршығыс аграрлық хабаршысы.– 2019.– Т.3. –№51.–Б.90-96.
  10. 10. Gunter S.A. Effects of supplementary selenium source on the performance and blood measurements in beef cows and their calves/ S.A.Gunter, P.A.Beck, J.K. Phillips // J Anim Sci. –2003. –Vol. 81(4). –Р.856-864.
  11. 11. Монгалев Н.П. Сиырлардың эстральды цикліндегі лейкоцитоздың функционалды маңызы/ Н.П. Монгалев, М.Ф. Борисенков // Ветеринарияның өзекті мәселелері.–2016.–Т.4. – №32.–Б.3-8.
  12. 12.Сорокина С.А. Эритроциттер және олардың деңгейінің қашарлар ағзасындағы металдармен және металоидтармен өзара байланысының ерекшеліктері / С.А. Сорокина, М.А. Дерхо// Н.Э. Бауман атындағы Қазан мемлекеттік ветеринарлық медицина академиясының ғылыми жазбалары.. –2022. –Т. 249. –№ 1. –Б. 197-204.
  13. 13.Licinio J. The neuroimmune-endocrine axis: pathophysiological implications for the central nervous system cytokines and hypothalamus-pituitary-adrenal hormone dynamics/ J.Licinio, P.Frost // Braz J Med Biol Res.– 2000.– Vol.33(10). –Р.141-148.
  14. 14.Funasaka N. Long-term monitoring of circulating progesterone and its relationship to peripheral white blood cells in female false killer whales Pseudorcacrassidens / N. Funasaka, M.Yoshioka, K. Ueda, H.Koga, M.Yanagisawa, S.Koga, K.Tokutake //J Vet Med Sci. –2018. –Vol.80(9). –Р. 1431-1437.
  15. 15. Song C.Z. Erythrocyte-based analgesic peptides/ C.Z.Song, Q.W.Wang, C.C. Song // RegulPept. –2013. –Vol.180.–Р.58-61.
  16. 16.Sawyer G. Measuring wool cortisol and progesterone levels in breeding maiden Australian merino sheep (Ovisaries) / G.Sawyer, D.Webster, E.Narayan // PLoS One. –2019. –Vol.14(4). –Р.1-9
  17. 17. След А.Н. Лейкоциттер және олардың кортизолмен және сауылмайтын сиырлардың ағзасындағы прогестеронмен байланысының ерекшеліктері/ А.Н. След, М.А. Дерхо// ОМАУжаңалықтары. –2019. –№ 1(75).–Б. 133-136.
  18. 18.Ndiaye K. Progesterone effects on lymphocytes may be mediated by membrane progesterone receptors / K. Ndiaye, D.H. Poole, S.Walusimbi, M.J. Cannon, K. Toyokawa, S.W. Maalouf, J.Dong, P.Thomas, J.L. Pate // J ReprodImmunol. –2012. –Vol. 95(1-2). –Р.36-48.

Citation Links

[1]2022. THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS. Izdenister natigeler. 2 (94) (Jun. 2022), 5–12. DOI:https://doi.org/10.37884/2-2022/01.
(1)THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS. Izdenister natigeler 2022, No. 2 (94), 5-12. https://doi.org/10.37884/2-2022/01.
THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS. (2022). Izdenister Natigeler, 2 (94), 5-12. https://doi.org/10.37884/2-2022/01
THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS. Izdenister natigeler, [S. l.], n. 2 (94), p. 5–12, 2022. DOI: 10.37884/2-2022/01. Disponível em: https://agrosoil.kaznaru.edu.kz/index.php/research/article/view/121. Acesso em: 15 sep. 2026.
“THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS”. 2022. Izdenister Natigeler, no. 2 (94) (June): 5-12. https://doi.org/10.37884/2-2022/01.
“THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS” (2022) Izdenister natigeler, (2 (94), pp. 5–12. doi:10.37884/2-2022/01.
[1]“THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS”, Izdenister natigeler, no. 2 (94), pp. 5–12, Jun. 2022, doi: 10.37884/2-2022/01.
“THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS”. Izdenister Natigeler, no. 2 (94), June 2022, pp. 5-12, https://doi.org/10.37884/2-2022/01.
“THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS”. Izdenister natigeler, no. 2 (94) (June 28, 2022): 5–12. Accessed September 15, 2026. https://agrosoil.kaznaru.edu.kz/index.php/research/article/view/121.
1.THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS. Izdenister natigeler [Internet]. 2022 Jun. 28 [cited 2026 Sep. 15];(2 (94):5-12. Available from: https://agrosoil.kaznaru.edu.kz/index.php/research/article/view/121
1.THE ROLE OF CORTISOL AND PROGESTERONE IN THE FORMATION OF RESPIRATORY BLOOD PROPERTIES IN HOLSTAN HEIFERS. Izdenister natigeler. 2022;(2 (94):5-12. doi:10.37884/2-2022/01